First, add the "Microsoft.Office.Interop.Excel" assembly reference in your project. Please make sure your project uses .Net Framework 4.0
Microsoft.Office.Interop.Excel.Application ExcelApp = new Microsoft.Office.Interop.Excel.Application(); ExcelApp.Application.Workbooks.Add(Type.Missing); // Change properties of the Workbook ExcelApp.Columns.ColumnWidth = 20; // Storing header part in Excel for (int i = 1; i < dataGridView1.Columns.Count + 1; i++) { ExcelApp.Cells[1, i] = dataGridView1.Columns[i - 1].HeaderText; } // Storing Each row and column value to excel sheet for (int i = 0; i < dataGridView1.Rows.Count - 1; i++) { for (int j = 0; j < dataGridView1.Columns.Count; j++) { ExcelApp.Cells[i + 2, j + 1] = dataGridView1.Rows[i].Cells[j].Value.ToString(); } } MessageBox.Show("Excel file created , you can find the file D:\\Employee Data.xlsx"); ExcelApp.Visible = true; ExcelApp.ActiveWorkbook.SaveCopyAs("D:\\Employee Data.xlsx"); ExcelApp.ActiveWorkbook.Saved = true; Marshal.FinalReleaseComObject(ExcelApp);